Tambre presents four fertility research studies at the COGI 2025 Congress in Rome

When someone or a couple is trying to become parents and it doesn’t happen, they look for much more than treatment. They look for answers, trust, and a team capable of combining science with genuine human understanding. At Tambre, that search for answers goes far beyond the consultation room – our work continues in the laboratory and at international scientific congresses, where the future of reproductive medicine is shaped.

This year, Fundación Tambre is taking an active role at the International Congress of Gynecology and Obstetrics COGI 2025 in Rome, presenting four scientific studies in oral format. These will be delivered by Tambre’s Medical Director, Dr. Laura García de Miguel, and Tambre’s Scientific Advisor, Dr. José Antonio Horcajadas. These studies not only expand current knowledge in fertility, but also reflect our firm belief that innovation must be a daily practice.

Four scientific perspectives on the path to pregnancy

The studies presented by Fundación Tambre address some of the most relevant questions in assisted reproduction today, ranging from the role of the microbiome and the immune system to the impact of maternal and paternal age on embryo quality.

Endometrial microbiome

The first study explored how the endometrial microbiome – the community of microorganisms living in the uterus – can influence embryo implantation. Findings showed that, after a personalised antibiotic and probiotic treatment, patients with an altered microbiome achieved pregnancy rates comparable to those with a balanced microbiome.

Maternal age and immune system (NK cells)

The second study looked at maternal age and its relationship with Natural Killer (NK) cells, which are part of the immune system. Researchers observed that older women tended to have higher NK cell levels, something that may help explain certain cases of implantation failure or recurrent pregnancy loss.

Paternal age and sperm quality

The third study focused on the male factor, analysing how paternal age and different sperm characteristics affect the formation of chromosomally normal embryos. Although the impact is milder than maternal age, the results showed a progressive decrease in genetic quality as paternal age increases.

Embryo quality and oocyte vitrification

The final study examined which factors best predict embryo quality when using vitrified (frozen) oocytes. It confirmed that the woman’s age at the time of freezing is the most decisive factor, while storage time does not affect outcomes.

Together, these studies reinforce a clear idea: reproductive medicine works best when science and personalised care evolve hand in hand.

Fundación Tambre was created to promote research, education, and scientific outreach. Its mission is to transform the knowledge generated in daily clinical practice into studies that have a real impact on patient outcomes.

In a field where treatments must be tailored to each individual situation, research becomes essential for understanding why pregnancy doesn’t always occur and how we can improve every step of the journey.

“Every step forward we make in the lab translates into better outcomes for our patients. Research helps us personalise treatments, shorten the time to pregnancy, and increase success rates.”

Dr. Laura García de Miguel, Medical Director at Tambre

Fundación Tambre leads projects in areas such as reproductive genetics, immunology, and the study of the microbiome, always with a clear goal: turning scientific knowledge into better care for our patients.

From the laboratory to the consultation room

One of Tambre’s strengths is the ability to quickly apply scientific findings when they show clinical benefit. For instance, the study on the endometrial microbiome has helped reinforce the use of uterine environment analysis in cases of recurrent implantation failure or miscarriage.

Similarly, research on maternal age, egg quality, and immune factors has contributed to refining treatment protocols, allowing us to personalise therapies, select embryos more precisely, and provide clearer guidance to patients.

Because research is, above all, a way to better understand every reproductive story and to offer more effective and compassionate solutions.

We have prepared a short video so you can see how research is part of our everyday work at Tambre.

Tambre’s participation in international congresses such as COGI shows not only our commitment to research, but also our determination to share knowledge with the global scientific community. These events are vital for validating results, comparing methodologies, and learning from collective experience.

Behind each study lies months, and often years, of coordinated work among doctors, embryologists, immunologists, and molecular biologists, as well as the contribution of patients who trust the research process and help advance medicine.

This blend of rigour, transparency, and humanity is what defines the Tambre model. Because trust grows when patients know they are supported by a team that never stops asking “why” and “how can we make this better?”.

Technological advances – such as artificial intelligence for embryo selection, time-lapse incubators, or genetic testing platforms – are powerful tools. At Tambre, we use them with a clear purpose: to improve the chances of success while maintaining a deeply human approach.

That is why Fundación Tambre not only publishes scientific results but also translates them into real changes in clinical protocols, staff training, and, ultimately, patient experience. That is the difference between researching and truly transforming.

Science that brings hope to your story

At Tambre, we believe that scientific progress matters only when it helps more people achieve their dream of becoming parents. Taking part in congresses like COGI is part of a long-standing commitment that goes beyond recognition – it is our way of keeping alive the pioneering spirit that has guided the clinic since 1978.

More than four decades later, that spirit remains our driving force: to research, innovate, and care. Because behind every study, there is a shared goal: turning today’s hopes into tomorrow’s heartbeats.

If you are considering starting your fertility journey and want a clinic where science and empathy go hand in hand, Tambre is here to support you with personalised care and a team committed to researching for you.

You can also learn more about our main fertility treatments and how we adapt them to each individual situation.