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Life-changing science: Tambre presents 4 fertility studies at ESHRE 2025 in Paris

fertility studies Tambre ESHRE 2025

Just over a year ago, we attended a very special edition of the ESHRE congress in the Netherlands, commemorating its 40th anniversary. For Tambre it was an unforgettable event: we shared knowledge, presented research and returned with the certainty that we were on the right track. Today, with lasting positive impressions from that meeting, we are preparing to return stronger than ever to ESHRE 2025, which will take place in Paris, from 29 June to 2 July.

This year we doubled our scientific participation: we presented four studies developed by the Tambre Foundation, reinforcing our commitment to reproductive medicine based on research, clinical evidence and, above all, on the real impact this has on our patients.

What is ESHRE and why is it so important?

ESHRE (European Society of Human Reproduction and Embryology) is the leading scientific event in the field of fertility. It is one of the most influential events at international level, where the most relevant research in the sector is shared.

This edition will be held at the Paris Convention Centre – Paris Expo Porte de Versailles, one of the largest venues in Europe, in a city steeped in history, culture and science. It will be four intense days with more than 80 scientific sessions, debates, poster presentations, pre-congress courses and the latest advances in embryology, genetics, ovarian stimulation, fertility preservation and artificial intelligence, among others.

Four Tambre studies in Paris

At Tambre, we are committed to research as one of our pillars and our way of understanding reproductive medicine. Thanks to the Tambre Foundation, we are constantly working on projects that arise from daily clinical practice, the real challenges faced by our patients, and the constant desire to improve every step of treatment.

This year, our studies address key areas for treatment success:

1. Is sperm DNA fragmentation always an obstacle?

In this study, Tambre’s team analysed more than 300 egg donation cycles to see if a high level of sperm DNA fragmentation negatively affects fertilisation or embryo development.
What did we find? When advanced sperm selection techniques are applied, even cases with high fragmentation can result in viable, chromosomally normal embryos. This brings peace of mind to many couples facing this diagnosis.

Sperm Samples with elevated Double-Strand DNA Fragmentation demonstrate similar fertilization outcomes to Low Fragmentation when treated: A Retrospective Analysis of egg donor cycles with PGT-A

A. Zavala-García, S. Cortés, C. Andrés, S. Ruiz, Á. Cayado; JA Horcajadas; H. Izquierdo, L. Ortega

2. The position of the inner cell mass of the embryo is also important.

Another study, led by Tambre’s lab, looks at how the position of the inner cell mass of the embryo – the part that will give rise to the future baby – can affect pregnancy rates following embryo biopsy for PGT-A.
It was observed that when this structure is kept within the protective zone of the embryo, pregnancy rates are significantly higher.
Furthermore, an adjustment in the assisted hatching technique is proposed to better protect this part of the embryo.

Impact of inner cell mass position on embryo implantation potential: Control strategies

C. Rodríguez, S. Cortés, C. Andrés, MA. Chávez, JA Horcajadas, L. Ortega

3. Reproductive immunology for more complex cases

The third paper explores the role of certain immune phenotypes (KIR) in women with unexplained infertility and repeated implantation failure or gestational loss.
The results show a statistically significant overrepresentation of specific immune profiles, reinforcing the hypothesis that the immune system may play a key role in these cases.

This study opens the door to further personalisation of treatments and a better understanding of what remains unexplained.

Increased prevalence of specific KIR phenotypes in a population of unexplained infertility with implantation failure and recurrent pregnancy loss: A retrospective study

A. Zavala-García, H. Izquierdo, L. Serrano-Palomo, J.A. Horcajadas, S. Padure

 4. Eight years of watching egg vitrification evolve

The fourth study analyses clinical and demographic trends in egg vitrification between 2015 and 2023, with data from almost 1,000 patients at Tambre. It confirms a progressive decrease in the age of vitrification, a growing international demand and a clear relationship between ovarian reserve and egg survival rate.

Preserve sooner, be better informed, decide freely. This study consolidates Tambre’s role as a benchmark in fertility preservation.

Trends in Oocyte Vitrification: Patient Demographics and Outcomes from 2015 to 2023

Á. Llaneza, A. Bullido, C. Andrés, S. Cortés, L. Serrano, J.A. Horcajadas

 

A new fertility clinic in Alicante, a new stage: Tambre Alicante

This year 2025 is also a special year for another reason. In May we opened Tambre Alicante, our second clinic in Spain. A space facing the sea, in one of the most touristy and accessible areas of the country, designed to welcome patients from all over the world with the same medical, scientific and human guarantees that have made Tambre an international benchmark.

Tambre Alicante was created with a strong commitment to excellence and ongoing research, replicating the collaboration model of the Tambre Foundation with universities and scientific institutions. In the Mediterranean city, we also promote projects that respond to the challenges of current fertility and offer real, immediate and personalised solutions.

How does all this benefit you?

If you are in treatment -or if you are considering it-, we want you to know that none of this is alien to your story. The science we develop at Tambre is science for you.

Each study we present in Paris can be translated into a concrete improvement: a more precise diagnosis, a more adapted treatment, a higher implantation rate, a reduction in the number of cycles required, a more humane experience with more certainty.

Science has a human face at Tambre

We continue to actively participate in the world’s most important congresses because our commitment to reproductive medicine is not just to implement protocols, but to improve them every day.

Want to know how these developments can help you?

We are here to accompany you, to explain, to listen to you. Because at Tambre, dreams have their own name. And yours is the next one.